The Congress "Osteoporosis and alterations of bone mineral metabolism in the general population and in chronic kidney disease", now in its 6th edition, will take place in Padua on 22-23-24 March 2023. This edition, after the one held in April, will allow us to proceed on the path of a recovery that hopefully will continue and not find the difficulties of the last two years. Skeletal fragility is one of the major complications in the general population but also in what is termed a systemic disorder of mineral metabolism in chronic kidney disease (Chronic Kidney Disease - Related Bone and Mineral Disease: CKD-MBD). Furthermore, considering the high mortality rate associated to this complication, it is necessary to implement new prevention, diagnosis and therapy strategies in clinical practice for a correct and prompt management of fragility fractures.

The Congress, also in this edition, offers a rich and articulated programme of various sessions: bone and diabetes, bone and cardiovascular link, bone and dialysis, as well as a focus on vit. K and vit. D and their fundamental role on "bone quality" for bone health. In addition, an up to date will be made on known and established drugs for the treatment of secondary hyperparathyroidism (etelcalcetide), and/or for the prevention of fragility fractures (denosumab and romozosumab); new old erythropoietins, new chelators and new vit. D (slow release) for the prevention and treatment of hyperparathyroidism and also in CKD not on dialysis.

Also in this edition there will be practical sessions dedicated to: ultrasound of the parathyroid glands, REMS, bone biopsy, and microindentation with the aim of providing participants with an in-depth study and an update in clinical practice, useful for consolidating a correct approach to diagnosis and follow-up. up in specific clinical settings (hyperparathyroidism, CKD-MB, and osteoporosis).

Finally, as always, there will be a session dedicated to young people, poster session and interactive session, with clinical cases, to stimulate and involve more and more young doctors and trainees to approach the diseases of mineral metabolism and fracture pathology even in patients with CKD.

The objective of the congress will therefore be to guarantee to all participants an in-depth study and therefore an educational growth on prevention, diagnosis and therapy of osteoporosis in the general population and in chronic kidney disease on the basis of the most recent evidence in the literature, but also to offer the tools necessary to create a fruitful multidisciplinary collaboration, essential to improve the care of our patients.

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WEDNESDAY, MARCH 22    

 12.00 - Welcome coffee and registration of participants

INTERACTIVE THEORETICAL-PRACTICAL COURSE ON INSTRUMENTAL DIAGNOSTICS OF SKELETAL FRAGILITY IN THE GENERAL POPULATION AND IN CHRONIC KIDNEY DISEASE PATIENTS

Theoretical session
Chairs: Alberto Bazzocchi, Sandro Giannini, Paolo Luca Lentini

13.00 - Ultrasound of the parathyroid glands. From diagnosis to follow-up of secondary hyperparathyroidism: it can become a routine tool
Mauro Dugo, Ilaria Petrucci
13.30 - Prediction of fracture risk, vascular calcification and use of REMS
Davide Gatti
14.00 - Bone biopsy from the past to the present: the follow-up can become a reality
Maria Fusaro, Maurizio Gallieni

14.30 - Discussion

14.40 - Plenary lecture 1
Monitoring bone quality in CKD

Alberto Bazzocchi

15.05 - We learn while sipping a coffee

Practical session
Participants will be divided into 5 groups that will rotate to participate in the practical sessions:
- Ultrasound of parathyroid glands in patients on dialysis and in patients with kidney transplant
- REMS
- The bone biopsy technique: virtual models and potential new strategies (with video demonstration)

17.15 - Statistics session
The statistician descends from the chair and enters the audience: questions and answers with the participants on recent trials in MBD
Giovanni Corrao, Giovanni Tripepi

18.35 - Adjourn

THURSDAY, MARCH 23

8.30 - OFFICIAL OPENING OF THE CONGRESS AND GREETINGS FROM THE AUTHORITIES
Maria Fusaro, Giovanni Tripepi, Giovanni Corrao, Mario Plebani, Francesca Mallamaci, Fabio Recchia

SESSION I
EXPERT DEBATE: SWEET BONE

Chairs: Maura Ravera, Roberto Vettor

9.15 - Update for the definition of a therapeutic algorithm on the use of recently acquired oral antidiabetics in the general population and in patients with chronic kidney disease
Paola Fioretto, Luca De Nicola

9.45 - Discussion

9.55 - Oral hypoglycemic agents and impact on skeletal frailty: how to prevent it in the general population and in chronic kidney disease

Cristiana Cipriani, Giuseppe Cianciolo

10.25 - Discussion

SESSION II
HOW HIGH THE BONE CAN FLY
Chairs: Maria Luisa Brandi, Serge Ferrari   

Two-way microphone  
10.35 - The astronaut does not live only on bone density: the role of Bone Quality – Maria Grano

10.50 - Potential vitamin support in space: what K in flight does – Maria Fusaro

11.05 - Discussion

11.15 - Coffee break

*11.30 - Clinical Practice Award “Roberta Marcon”
Introduction: Maria Fusaro, Francesca Mallamaci, Silvia Colucci


*POSTER SESSION

Chairs: Luisella Cianferotti, Carlo Alfieri

*12.15 - Oral communication of the first three classified posters- Auditorium

*12.45 - Lunch Poster – Agorà Hall

Chairs: Andrea Galassi, Silverio Rotondi, Silvia Colucci

SESSION III 
A JOURNEY BETWEEN BONE AND VASCULAR HEALTH
Chairs: Maria Fusaro, Serge Ferrari, Mario Plebani

14.00 - Plenary lecture 2
New diagnostic panel for high and low bone turnover in clinical practice of patients with CKD-MBD: from CKD to renal transplantation
Giuseppe Cianciolo

Two-way microphone
14.25 - Etelcalcetide: from bone biopsy to clinical practice
Thomas Nickolas
14.40 - Eternity-Ita Study: like a cat on the ring road
Giovanni Tripepi

14.55 - Plenary lecture 3
Dilemma: continuous or not continuous treatment in osteoporosis patients with or without CKD
Serge Ferrari

15.20 - Discussion

SESSION IV 
ONCO-NEFROLOGY
Chairs: Antonella Brunello, Laura Cosmai

15.30 - Plenary lecture 4
Bone metastases: what differences in the therapeutic approach between subject with normal renal function and patients with chronic kidney disease
Francesco Bertoldo

15.50 - Coffee break

SESSION V
BONE AND DIALYSIS

Chairs: Mario Cozzolino, Sandro Mazzaferro

16.05 - The progression of vascular calcifications: which score to use and how to slow it down
Antonio Bellasi

16.25 - Bone in dialysis is better at home: home dialysis (peritoneal and hemodialysis) and skeletal fragility
Roberto Russo

16.45 - Plenary lecture 5
Vertebral fractures in general population and in CKD. How to diagnose them and why
Jordi Bover

17.10 - Discussion

SESSION VI
RESIDENTS SECTION: CLINICAL CASE QUIZ
Chairs: Giuseppe Cianciolo, Sandro Giannini, Laura Cosmai

17.20 - Complex clinical cases
Simona Barbuto, Althea Cossettini, Giulia Re Sartò

17.50 - Discussion

SESSION VII
EXPERT DEBATE: LIPIDS IN CKD-MBD
Chairs: Francesca Mallamaci, Vincenzo Panuccio

Dyslipidemias in normal subjects and in patients with chronic kidney disease
Maura Ravera, Alberto Zambon

18.25 Discussion

18.35 Adjourn

Maria Fusaro, Giovanni Tripepi

FRIDAY, MARCH 24
SESSION VIII
FONDAZIONE ITALIANA DEL RENE
Chair: Maura Ravera

8.30 - Introducing FIR
Dario Gozzi, Massimo Morosetti

SESSION IX
FOCUS OF RARE DISEASES IN BONE MINERAL METABOLISM
Chairs: Serge Ferrari, Salvatore Minisola

8.45 - Plenary lecture 6
Hypophosphatasia: A Disorder with Bone and Kidney Complications
Maria Luisa Brandi

9.10 - Discussion

SESSION X
DEBATE: BONE AND ESA

Chairs: Fabio Malberti, Roberto Minutolo

9.20 - ESA: add a seat at the table that there is an extra HIF

Francesco Locatelli

9.30 - But how do ESA and HIF relate t bone?
Lucia Del Vecchio

9.40 - Discussion

9.50 - Coffee break

SESSION XI
THE SUPPLEMENTATION OF VITAMIN D: FROM A GUARANTEE FOR THE BONE TO NEW POTENTIAL TARGETS
Chairs: Iacopo Chiodini, Maria Fusaro, Fabio Vescini

10.10 - Cholecalciferol, calcifediol, calcitriol and COVID

Salvatore Minisola

10.30 - Medicine goes faster than society: Vitamin D and transgender Dyslipidemias in normal subjects and in patients with chronic kidney disease
Andrea Garolla

Expert Debate: Vitamin D and menopause

10.50 - Management of osteoporosis in menopause as a consolidated figure in the general population of Cinderella in CKD (she can become a princess)
Andrea Giusti, Maria Cristina Mereu

11.20 - Discussion

11.30 - Plenary lecture 7
Remarkable value vitamin D use: not only PTH – ALP an old friend forgot
Mathias Haarhaus

11.55 - Discussion

* 12.05 - Award “Elena Lucrezia Cornaro”
Introduction: Maria Fusaro, Maria Luisa Brandi, Francesca Mallamaci, Fabio Recchia, Giovanni Tripepi

12.25 - Lunch

Debate
Chairs: Andrea Giusti, Maria Fusaro

13.30 - Romosozumab: from numbers to bone and vascular, where is the benefit and where is the risk
Giovanni Tripepi, Serge Ferrari

SESSION XII
VITAMIN D: FROM REAL LIFE TO INNOVATION
Chairs: Maurizio Gallieni, Sandro Mazzaferro, Martina Zaninotto

13.55 - Plenary lecture 8
Vitamin D and KDIGO: re-thinking according to data from real-life
Markus Ketteler
14.20 - Plenary lecture 9
The management of vitamin D in pre-dialysis: what innovative approaches we are acquiring

Mario Cozzolino

14.45 Complex clinical case
Discussant: Luisella Cianferotti, Fabio Vescini
The bone does not live on calcium alone
Sandro Giannini

15.50 - Discussion

16.00 - Take home messages and adjourn
Maria Fusaro, Giovanni Tripepi

* Non-CME session

Enrollment in the course can only be done through the online procedure, no new registrations will be accepted at the congress venue.

The Italian will be the official language.

For access to the conference spaces, AccMed recommends adhering to the following safety rules:

• do not enter the conference spaces with a body temperature above 37.5
• maintain interpersonal distance
• wear the FFP2 mask covering the nose and mouth for the entire duration of the activity
• frequently disinfect hands with special hydroalcoholic gels

You can find further details on the conduct of the event and related security measures here: https://fad.accmed.org/sicurezza

Questa attività è riservata a un numero limitato di partecipanti.

La quota di partecipazione è:

• Medici - registration fee doctors € 180.00
• Biologi/fisioterapisti- biologists/phisioterapists € 120.00
• Dietisti/tecnici - dieticians/technicians € 120.00
• Under 40 € 0.00

Per i criteri di eleggibilità e altre informazioni sulle quote ridotte (qualora previste), contattare info.bologna@accmed.org.

Per partecipare all’evento è necessario completare la procedura di iscrizione (incluso il pagamento della quota applicabile) entro il 15/03/2023. Il pagamento è effettuabile online esclusivamente con Carte di Credito o Paypal.

Nel caso non venga raggiunto il numero minimo di iscritti previsto, Accademia si riserva la facoltà di annullare l’attività. In questo caso Accademia procederà alla opportuna comunicazione e al totale rimborso delle quote di partecipazione.
In caso di rinuncia, si prega di informare tempestivamente Accademia. Se la rinuncia avviene entro il 10° giorno precedente la data di inizio dell’evento, la quota versata sarà restituita con la detrazione del 30%. Se la rinuncia avviene dopo tale scadenza, l’utente non avrà diritto ad alcun rimborso.

The credit certification for the webinar is subject to:

• Professions/specializations should correspond to those which have been accredited for CME
• attendance at the 90% of the event
• the completion of the Meeting evaluation online form
• completion of the final test (at least 75% of correct answers). 1 attempt admitted. The test and the meeting evaluation form must be completed within 3 days from the end of the event.

Contenuti tecnico-professionali (conoscenze e competenze) specifici di ciascuna professione, di ciascuna specializzazione e di ciascuna attività ultraspecialistica, ivi incluse le malattie rare e la medicina di genere